Nimesulide 100 mg + Phenylephrine 10 mg + Cetirizine 5 mg + Caffeine 30 mg Tablet

Indication

⚙️ Mechanism of Action (Each Component)

1️⃣ Nimesulide (100 mg)

• Class: NSAID (preferential COX-2 inhibitor)
• Action:
  • Inhibits prostaglandin synthesis → ↓ pain, ↓ fever, ↓ inflammation
• Extra:
  • Also has mild anti-oxidant and anti-histaminic effects

2️⃣ Phenylephrine (10 mg)

• Class: α1-adrenergic agonist (decongestant)
• Action:
  • Causes vasoconstriction in nasal mucosa → reduces swelling → opens nasal passages
• Onset: Fast (within ~30–60 min)

3️⃣ Cetirizine (5 mg)

• Class: 2nd-generation H1 antihistamine
• Action:
  • Blocks histamine receptors → ↓ sneezing, itching, rhinorrhea
• Advantage:
  • Less sedation compared to older antihistamines (but mild drowsiness still possible)

4️⃣ Caffeine (30 mg)

• Class: CNS stimulant / adenosine receptor antagonist
• Action:
  • Enhances analgesic effect of NSAIDs
  • Reduces fatigue & drowsiness
  • Improves alertness

Dream Cold N Tablet

📌 Therapeutic Uses (Detailed)

✔️ Upper Respiratory Conditions

• Common cold
• Viral flu
• Allergic rhinitis
• Sinusitis

✔️ Symptom Relief

• Fever
• Headache (including sinus headache)
• Body ache / myalgia
• Nasal congestion
• Sneezing & runny nose
• Fatigue associated with illness

Dream Cold N Tablet

💊 Dosage (Typical Adult)

• Usually: 1 tablet 1–2 times daily after food
• Duration: Short-term use (3–5 days)
  👉 Always as per doctor’s advice

Dream Cold N Tablet

⚠️ Safety & Warnings (Important)

🚫 Nimesulide-related

• Risk of liver toxicity → avoid prolonged use
• Not recommended in children <12 years

🚫 Phenylephrine-related

• May increase:
  • Blood pressure
  • Heart rate
• Avoid in:
  • Hypertension
  • Heart disease
  • Hyperthyroidism

🚫 Cetirizine-related

• May cause:
  • Mild drowsiness
  • Dry mouth

🚫 Caffeine-related

• Can cause:
  • Restlessness
  • Insomnia
  • Palpitations

Dream Cold N Tablet

Contraindication

Nausea, Vomiting, Insomnia (difficulty in sleeping), Dizziness, Impaired coordination, Headache, Sedation, Inability to concentrate, Irritability, Tremors, diarrhoea, Dryness in mouth, Fatigue, Blurred vision.

Storage

Cool & Dry Place

Dosage

As directed by a Medical Practitioner or Physician.