Disodium Hydrogen Citrate 1.37  gm Syrup

# Product Overview (Calurinz Syp)

• Generic Name: Disodium Hydrogen Citrate

• Concentration: Typically 1.37 g per 5 ml (standard syrup formulation)

• Pharmacological Class: Urinary Alkalizer

# Mechanism of Action (How it works)

(Calurinz Syp)

Disodium Hydrogen Citrate is metabolized in the body into bicarbonate ions.

1. Systemic Effect: It increases the alkali reserve in the blood.

2. Urinary Effect: The excess bicarbonate is excreted by the kidneys into the urine.

3. Result: This raises the pH of the urine, making it less acidic. By neutralizing the acid, it helps dissolve uric acid stones and prevents the crystallization of certain salts.

# Common Uses

(Calurinz Syp)

• Urinary Tract Infections (UTI): It relieves the “burning sensation” during urination by neutralizing acidic urine that irritates the inflamed lining of the urethra.

• Kidney Stones: Used to prevent and treat uric acid stones and calcium oxalate stones (uricosuric therapy).

• Gout: It aids in the excretion of uric acid, helping to lower blood levels that cause joint pain.

• Acidosis: Occasionally used to manage metabolic acidosis caused by certain kidney diseases.

## Side Effects

(Calurinz Syp)

While generally well-tolerated when taken with plenty of water, some users may experience:

Common Side Effects

(Calurinz Syp)

• Gastrointestinal Upset: Nausea, vomiting, or stomach pain.

• Diarrhea: It can have a mild laxative effect in some individuals.

• Flatulence: Bloating or gas.

Serious Side Effects (Rare)

• Electrolyte Imbalance: Excessive use can lead to low potassium (hypokalemia) or high sodium levels.

• Metabolic Alkalosis: Over-alkalizing the blood, which can cause muscle twitching or confusion.

# Important Administration Tips

(Calurinz Syp)

• Dilution is Key: This syrup should always be diluted in a glass of water (approx. 100-200 ml) and sipped slowly to avoid stomach irritation.

• Hydration: Drink plenty of fluids throughout the day to help the kidneys flush out crystals.

• Precautions: Use with caution if you have high blood pressure, heart failure, or kidney impairment, as this medication contains a significant amount of sodium.

[!CAUTION] This information is for educational purposes. Please consult a healthcare professional before starting this medication, especially if you are on a low-sodium diet or taking other medications like tetracyclines or lithium.